YAZ was approved by FDA for use as a hormonal contraceptive to prevent pregnancy, treatment of moderate acne (acne vulgaris) and a PMDD (Premenstrual Dysphoric Disorder). Regrettably, PMDD has been mistaken with the more common phenomena – PMS (Premenstrual Syndrome). However, they are not identical. PMS is a group of symptoms linked to the menstrual cycle women experience.
On the other hand, PMDD, is recognized by the DSM-IV (Diagnostic & Statistical Manual of Mental Disorders) and requires five (5) or more of the criteria below be present in most menstrual cycles during a one (1) year period of time during specific time frames related to woman’s menstrual cycle.
- markedly depressed mood, feelings of hopelessness, or self-deprecating thoughts
- marked anxiety, tension, feelings of being “keyed up”, or “on edge”
- marked affective lability (e.g., feeling suddenly sad or tearful or increased sensitivity to rejection)
- persistent and marked anger or irritability or increased interpersonal conflicts
- decreased interest in usual activities (e.g., work, school, friends, hobbies)
- subjective sens of difficulty in concentrating
- lethargy, easy fatigability, or marked lack of energy
- marked change in appetite, overeating, or specific food cravings
- hypersomnia or insomnia
- a subjective sens of being overwhelmed or out of control
- other physical symptoms, such as breast tenderness or swelling, headaches, joint or muscle pain, a sensation of “bloating”, weight gain